Morphology of White Blood Cell

LET'S STUDY ABOUT WHITE BLOOD CELL

As everyone know that white blood cell(leukocytes) is one the main component in our blood besides platelets and red blood cell. They produced in bone marrow and store in our blood and lymphatic system.

For healthy body, white blood cells(WBC) in our body range between 4500-11000 per cubic millimeter of blood. The general characteristics of our WBC are they lack of haemoglobin, colourless, have nuclues, irregular like shaped that helps them to squeeze through our blood vessels. Don't think due to their weird shape, we misunderstand them as foreign materials in our blood. They are the one that responsible battle with viruses, bacteria and other foreign invader in our body. Furthermore, they also responsible produce antibodies for our body so that we stay healthy☺☺

Next, let study more about types of white blood cells. Do you know that our WBC can be divided into 2 group, GRANULOCYTES and AGRANULOCYTES . 

Types of  white blood cells

GRANULOCYTES

• meaning: the presence of  distinct cytoplasmic granulation( have granules)
• have 3 types: neutrophils, basophils, eosinophils

CHARACTERISTICS OF :-

a) NEUTROPHILS

• most abundant type of WBC, making up 55-70% in our blood 
• spherical shaped with diameter 12-15µm
• nucleus with 2-5 lobes connected by fine filament
• transparent cytoplasm with pink/red granules
• immature neutrophils have band-shaped or horse-shoe shaped nucleus
• function against bacteria infection and inflammation through phagocytosis

Microscopic version of Neutrophils

b) EOSINOPHILS

• made in red bone marrow and are very rare in normal individuals, making up 2-4 of WBC
• have same size as neutrophils
• have bilobed nuclues, cytoplasm full with red-stained granules
• main function is to deal with parasitic infection and limiting inflammation

Microscopic version of Eosinophils

c) BASOPHILS

• the rarest WBC, making up less than 1% in our blood
• their cytoplasm full with dark-purple coloured granules
• have bilobed or trilobed nucleus that hard to see as they overlapped with granules
• they responsible deals with allergic reaction by secreting chemicals such as histamine, a marker of allergic disease that help control the body's immune respond

Microscopic version of Basophils

AGRANULOCYTES

• meaning: without the presence of distinct cytoplasmic granulation(no granules)
• have 2 types: monocytes, lymphocytes

CHARACTERISTICS OF :-

a) MONOCYTES

• the biggest WBC with kidney-shaped nucleus
• the only WBC that have irregular shaped
• have transparent cytoplasm with ground glass appearance and have vacuole
• have longer life span compare with other WBCs
• have phagocytosis function by binding to the pathogens and present them to T-cells

Microscopic version of Monocytes

b) LYMPHOCYTES

• type of WBC that fundamental importance in the immune system because they can determine the specific immune respond to any infectious microorganisms and foreign invaders
• their size is smaller than other white blood cells but larger than red blood cells
• make up roughly 20-40% of total number of WBC
• have transparent cytoplasm with round and big nucleus occupying most of cytoplasm
• can be subdivided into 3 types:

Natural Killer Cells

• T-cells - to coordinate immune system,defense against bacteria & kill infected cell
• B-cells - produce antibodies that bind bacteria & destroy them
• Natural Killer Cells - kill cells that infected and becoming cancerous cell by nature

THAT'S ALL FROM ME

HOPEFULLY THIS POST IS BENEFICIAL FOR YOU☺☺☺☺☺